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Dihydro-β-erythroidine hydrobromide, Tocris Bioscience™

Catalog Number p-4783907
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Menge:
10 mg
50 mg
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
29734-68-7
C16H22BrNO3
356.26
GFIGWAJEIMHJJB-LINSIKMZSA-N
dihydro-beta-erythroidine hydrobromide, unii-ns1u03gc05, 2s,13bs-2-methoxy-2,3,5,6,8,9,10,13-octahydro-1h,12h-benzo i pyrano 3,4-g indolizin-12-one hydrobromide, dh?e, dihydro-?-erythroidine hydrobromide, 3, a-1,6-didehydro-14,17-dihydro-3-methoxy-16 15h-oxaerythrinan-15-one hydrobromide, 3beta-1,6-didehydro-14,17-dihydro-3-methoxy-16 15h-oxaerythrinan-15-one hydrobromide
11957537
COC1CC=C2CCN3C2(C1)C4=C(CC3)COC(=O)C4.Br
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
29734-68-7
C16H22BrNO3
356.26
GFIGWAJEIMHJJB-LINSIKMZSA-N
dihydro-beta-erythroidine hydrobromide, unii-ns1u03gc05, 2s,13bs-2-methoxy-2,3,5,6,8,9,10,13-octahydro-1h,12h-benzo i pyrano 3,4-g indolizin-12-one hydrobromide, dh?e, dihydro-?-erythroidine hydrobromide, 3, a-1,6-didehydro-14,17-dihydro-3-methoxy-16 15h-oxaerythrinan-15-one hydrobromide, 3beta-1,6-didehydro-14,17-dihydro-3-methoxy-16 15h-oxaerythrinan-15-one hydrobromide
11957537
COC1CC=C2CCN3C2(C1)C4=C(CC3)COC(=O)C4.Br

Beschreibung

α4β2, muscle type and Torpedo nAChR antagonist

Dihydro-β-erythroidine hydrobromide is a member of the Erythrina alkaloids, it is a competitive nicotinic acetylcholine receptor antagonist with moderate selectivity for the neuronal α4 receptor subunit (IC50 values are 0.19 and 0.37 μM for α4β4 and α4β2 receptors, respectively). Antagonizes behavioral effects of nicotine in vivo. Dihydro-β-erythroidine blocks excitation of striatal GABAergic neurons, which completely suppress polysynaptic inhibition between striatal cholinergic interneurons. Dihydro-β-erythroidine hydrobromide has antidepressive-like effects in mice (forced swim and mouse suspension). Orally bioavailable
Chemischer Name oder Material Dihydro-β-erythroidine hydrobromide
Menge 10 mg
Formelmasse 356.26
Reinheit (%) >98%
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