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EIF4A3 Mouse anti-Human, CoraLite 488, Clone: 1G6H9, Proteintech

Mouse Monoclonal Antibody

Marke:  Proteintech CL488-67740-100UL

Weitere Details : Netto-Gewicht : 0.00010kg

Artikelnummer. 17294756

  • 319.00 € / 100 Mikroliter
Verfügbar ab: 09-02-2023
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Beschreibung

Beschreibung

EIF4A3 is a component of the exon junction complex (EJC), which assembles near exon-exon junctions of mRNAs as a result of splicing. EJC proteins involves in postsplicing events, including mRNA export, cytoplasmic localization, and nonsense-mediated decay. Its RNA-dependent ATPase and RNA-helicase activities are induced by CASC3, but abolished in presence of the MAGOH/RBM8A heterodimer, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation. Besides, it involved in translational enhancement of spliced mRNAs after formation of the 80S ribosome complex and binds spliced mRNA in sequence-independent manner, 20-24 nucleotides upstream of mRNA exon-exon junctions

Spezifikation

Spezifikation

EIF4A3
Monoclonal
1000 μg/mL
Mouse
Primary
Rat, Mouse, Human
IgG2b
Immunofluorescence
1G6H9
CoraLite 488
100 μL
9775
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote