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EIF4A3 Mouse anti-Human, CoraLite 488, Clone: 1G6H9, Proteintech
Mouse Monoclonal Antibody
Marke: Proteintech CL488-67740-100UL
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
EIF4A3 is a component of the exon junction complex (EJC), which assembles near exon-exon junctions of mRNAs as a result of splicing. EJC proteins involves in postsplicing events, including mRNA export, cytoplasmic localization, and nonsense-mediated decay. Its RNA-dependent ATPase and RNA-helicase activities are induced by CASC3, but abolished in presence of the MAGOH/RBM8A heterodimer, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation. Besides, it involved in translational enhancement of spliced mRNAs after formation of the 80S ribosome complex and binds spliced mRNA in sequence-independent manner, 20-24 nucleotides upstream of mRNA exon-exon junctions
Spezifikation
EIF4A3 | |
Monoclonal | |
1000 μg/mL | |
Mouse | |
Primary | |
Human, Mouse, Rat | |
IgG2b |
Immunofluorescence | |
1G6H9 | |
CoraLite 488 | |
100 μL | |
9775 | |
Liquid |