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Thermo Scientific™ EZ-Link™ TFP Ester-PEG4-DBCO
An amine reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications. The crosslinker can be used to label a variety of amine containing molecules such as proteins, biomolecules, or small molecules.
206.00 € - 279.00 €
Spezifikation
| Chemische Reaktivität | Amin-Azid |
|---|---|
| Cleavable | Nein |
| Beschreibung | TFP-Ester-PEG4-DBCO |
| Molekulargewicht | 714,7 |
| PEGyliert | Ja |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
17514346
|
Thermo Scientific™
C20039 |
10 x 1 mg |
206.00 €
25 Milligramm |
Verfügbar ab: 10-06-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
|
17621586
|
Thermo Scientific™
C20043 |
10 x 1 mg |
279.00 €
10 Stück |
Verfügbar ab: 13-06-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
- An amine reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications
- The crosslinker can be used to label a variety of amine containing molecules such as proteins, biomolecules, or small molecules
- Once a protein or (bio)molecule is DBCO labeled, it can undergo a copper-free azide-alkyne cycloaddition reaction to form a stable triazole linkage with an azide labeled coupling partner
- Can be used to create diverse conjugates with the biorthogonal coupling between an alkyne and azide (supplied separately)
- The coupling or crosslinking procedure is typically done in two steps
- First, a protein or amine containing molecule is labeled with a DBCO group and excess crosslinker is removed
- Second, an azide containing moiety (prepared independently) is introduced into the same system as the DBCO moiety
- Labeling occurs under biological conditions without the introduction of any additional reagents such as a copper catalyst
- Ragent readily dissolves in water-miscible solvents for dilution into aqueous reaction mixtures
- TFP esters are more hydrolytically stable than NHS esters
Spezifikation
| Amin-Azid | |
| TFP-Ester-PEG4-DBCO | |
| Ja | |
| Nach Erhalt getrocknet bei -20 °C lagern. | |
| Nasses Eis | |
| Chemische Markierung | |
| TFP-Ester, DBCO | |
| 10 x 1 mg | |
| Standard, Einmalgebrauch | |
| Crosslinker |
| Nein | |
| 714,7 | |
| 17,9 Å | |
| Nicht ermittelt | |
| EZ-Link™ No-Weigh™ | |
| Heterobifunktional | |
| Mittel (10 bis 30 Å) | |
| DMF, DMSO | |
| Nein |