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HLA-B7 Monoclonal Antibody (BB7.1), PE, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Marke: Affymetrix eBioscience 12-5917-42
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
Description: This BB7.1 monoclonal antibody recognizes the human major histocompatibility complex MHC class I molecule HLA-B7, which is a member of the HLA-B family. MHC class I exists as a heterodimer composed of a specific alpha chain associated with a beta 2-microglobulin. MHC class I molecules are expressed on all nucleated cells. Applications Reported: This BB7.1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This BB7.1 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
HLA-B7 is one of the polymorphic proteins of human MHC Class I found on all nucleated cells. This surface protein is a heterodimer consisting of the specific transmembrane HLA-B chain paired with Beta-2 microglobulin. Classical MHC Class I molecules play a central role in adaptive immunity by presenting to T cells antigenic peptides derived either from the cell itself (classical presentation) or extracellular antigens (cross-presentation). The ligands of MHC class I include T cell receptor (TCR) and a costimulatory molecule CD8. Hundreds of HLA-B alleles have been described. Typing for these polymorphisms is routinely done for transplantation.Spezifikation
HLA-B7 | |
Monoclonal | |
5 μL/Test | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
P01889 | |
HLA-B | |
Papain solubilized HLA-B7 | |
100 Tests | |
Primary | |
Human | |
Antibody | |
IgG1 κ |
Flow Cytometry | |
BB7.1 | |
PE | |
HLA-B | |
A29 protein; antigen presenting molecule; AS; Aw-33; Aw-74; B-4901; B-5001; Bw-47; Bw-50; CDABP0067; class I MHC, HLA-B antigen; DAQB-90C11.16; epididymis secretory protein Li 83; FLJ26655; HEL-S-83; histocompatibility antigen; HLA A; HLA -B; HLA B-40011; HLA B44; hla b7; HLA class I antigen; HLA class I antigen HLA-B; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-30 alpha chain; HLA class I histocompatibility antigen, A-33 alpha chain; HLA class I histocompatibility antigen, A-74 alpha chain; HLA class I histocompatibility antigen, B alpha chain; HLA class I histocompatibility antigen, B-47 alpha chain; HLA class I histocompatibility antigen, B-50 alpha chain; HLA class I histocompatibility antigen, B-82 alpha chain; HLA locus; HLA molecule; HLAA; HLA-A; HLA-A locus alpha 2 domain; HLA-A null; HLA-A11; HLA-A33; HLA-Aw33.1; HLAB; HLA-B; HLA-B 1502; HLA-B alpha chain; HLA-B alpha | |
Mouse | |
Affinity chromatography | |
RUO | |
3106 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |