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HTR2A Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Thermo Scientific PA553111
Weitere Details : Netto-Gewicht : 0.02000kg
Beschreibung
Immunogen sequence: TIKSLQKEAT LCVSDLGTRA KLASFSFLPQ SSLSSEKLFQ RSIHREPGSY TGRRTMQSIS NEQ Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 97%.
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.Spezifikation
HTR2A | |
Polyclonal | |
Unconjugated | |
HTR2A | |
HTR2A, 5-HT2A, 5-HT-2A, 5-HT2a receptor, 5HT2A Receptor, 5-HT-2, 5-HT2A/2C, 5-HT2A/2C receptor, 5-HT2 receptor, HTR2, Serotonin 5-HT-2A receptor, Serotonin receptor 2A, Serotonin 2a receptor | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
3356 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P28223 | |
HTR2A | |
Recombit protein corresponding to Human HTR2A | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only