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ACROBiosystems Human 2B4 / CD244 / SLAMF4 Protein, Fc Tag
302.42 € - 2020.12 €
Spezifikation
Zugriffsnummer | NP_057466 |
---|---|
Molekulargewicht | 48.9 kDa |
Quelle | Human 2B4, Fc Tag (2B4-H5255) is expressed from human 293 cells (HEK293). It contains AA Cys 22 - Arg 221 (Accession # NP_057466). |
Immunogen | Cys 22 - Arg 221 |
Lagerungsbedingungen | -20°C |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15865847
|
ACROBiosystems
2B4-H5255-1MG |
1 mg |
2020.12 €
1 Milligramm |
Verfügbar ab: 07-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
15855847
|
ACROBiosystems
2B4-H5255-100UG |
100 μg |
302.42 €
100 Mikrogramm |
Verfügbar ab: 07-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.9 kDa. The protein migrates as 60-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_057466 | |
Human 2B4, Fc Tag (2B4-H5255) is expressed from human 293 cells (HEK293). It contains AA Cys 22 - Arg 221 (Accession # NP_057466). | |
-20°C | |
2B4 | |
Human | |
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 | |
HEK293 | |
Immune Checkpoint Proteins |
48.9 kDa | |
Cys 22 - Arg 221 | |
CD244,2B4,SLAMF4,NKR2B4,NAIL,h2B4 | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |