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ACROBiosystems Human 2B4 / CD244 / SLAMF4 Protein, His Tag
Marke: ACROBiosystems 2B4-H5224-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.1 kDa. The protein migrates as 35-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_057466 | |
100 μg | |
Cys 22 - Arg 221 | |
CD244,2B4,SLAMF4,NKR2B4,NAIL,h2B4 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
23.1 kDa | |
Human 2B4, His Tag (2B4-H5224) is expressed from human 293 cells (HEK293). It contains AA Cys 22 - Arg 221 (Accession # NP_057466). | |
-20°C | |
2B4 | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Immune Checkpoint Proteins |