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ACROBiosystems Human B7-H5 / Gi24 / VISTA Protein, Mouse IgG2a Fc Tag, low endotoxin
low endotoxin
Marke: ACROBiosystems B75-H5258-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 45.0 kDa. The protein migrates as 55-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
AAH20568.1 | |
100 μg | |
Phe 33 - Ala 194 | |
B7-H5,SISP1,Gi24,VISTA | |
Unconjugated | |
Mouse IgG Fc Tag | |
Less than 0.1 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
45.0 kDa | |
Human B7-H5, Mouse IgG2a Fc Tag, low endotoxin (B75-H5258) is expressed from human 293 cells (HEK293). It contains AA Phe 33 - Ala 194 (Accession # AAH20568.1). | |
-20°C | |
B7-H5 | |
Human | |
50 mM Tris, 100 mM Glycine, pH7.5 | |
HEK293 | |
Immune Checkpoint Proteins |