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ACROBiosystems Human B7-H7 / HHLA2 Protein, His Tag
N.V.
Spezifikation
Zugriffsnummer | NP_009003.1 |
---|---|
Molekulargewicht | 38.9 kDa |
Quelle | Human B7-H7, His Tag (B77-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ile 23 - Asn 344 (Accession # Q9UM44-1). |
Immunogen | Ile 23 - Asn 344 |
Lagerungsbedingungen | -20°C |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
16437199
|
ACROBiosystems
B77-H52H5-1MG |
1 mg |
N.V.
1 Milligramm |
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16427199
|
ACROBiosystems
B77-H52H5-100UG |
100 μg |
N.V.
100 Mikrogramm |
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Dieser Artikel erfordert eine Preisaktualisierung, bevor er bestellt werden kann. Fordern Sie hier einen Preis für diesen Artikel an. |
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Beschreibung
B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.9 kDa. The protein migrates as 48-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_009003.1 | |
Human B7-H7, His Tag (B77-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ile 23 - Asn 344 (Accession # Q9UM44-1). | |
-20°C | |
B7-H7 | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Immune Checkpoint Proteins |
38.9 kDa | |
Ile 23 - Asn 344 | |
B7-H7,HHLA2,B7 Homolog 7 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / µg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |