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ACROBiosystems Human CD30 / TNFRSF8 Protein, Fc Tag
MALS verified
314.52 € - 2020.12 €
Spezifikation
Zugriffsnummer | NP_001234.2 |
---|---|
Molekulargewicht | 64.6 kDa |
Quelle | Human CD30, Fc Tag (CD0-H5250) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2). |
Immunogen | Phe 19 - Lys 379 |
Lagerungsbedingungen | -20°C |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15836127
|
ACROBiosystems
CD0-H5250-100UG |
100 μg |
314.52 €
100 Mikrogramm |
Verfügbar ab: 24-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
15846127
|
ACROBiosystems
CD0-H5250-1MG |
1 mg |
2020.12 €
1 Milligramm |
Verfügbar ab: 24-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 64.6 kDa. The protein migrates as 90-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_001234.2 | |
Human CD30, Fc Tag (CD0-H5250) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2). | |
-20°C | |
CD30 | |
Human | |
50 mM Tris, 100 mM Glycine, pH7.5 | |
HEK293 | |
Immune Checkpoint Proteins |
64.6 kDa | |
Phe 19 - Lys 379 | |
TNFRSF8,CD30,D1S166E,Ki-1 | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |