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ACROBiosystems Human CTGF / CCN2 Protein, His Tag
Marke: ACROBiosystems CTF-H52H5-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.4 kDa. The protein migrates as 36-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_001892.1 | |
100 μg | |
Gln 27 - Ala 349 | |
CCN2,NOV2,HCS24,IGFBP8,IBP-8,IGFBP-8,IGF-binding protein 8 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |
37.4 kDa | |
Human CTGF, His Tag (CTF-H52H5) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Ala 349 (Accession # Q5M8T4-1). | |
-20°C | |
CTGF | |
Human | |
Tris with Potassium glutamate and Arginine, pH7.0 | |
HEK293 | |
Cytokines and Growth Factors |