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ACROBiosystems Human Osteoprotegerin / TNFRSF11B Protein, Fc Tag
217.74 € - 1463.68 €
Spezifikation
Zugriffsnummer | NP_002537 |
---|---|
Molekulargewicht | 70.2 kDa |
Quelle | Human Osteoprotegerin, Fc Tag (TNB-H5259) is expressed from human 293 cells (HEK293). It contains AA Glu 22 - Leu 401 (Accession # NP_002537). |
Immunogen | Glu 22 - Leu 401 |
Lagerungsbedingungen | -20°C |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15867847
|
ACROBiosystems
TNB-H5259-1MG |
1 mg |
1463.68 €
1 Milligramm |
Verfügbar ab: 07-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
15857847
|
ACROBiosystems
TNB-H5259-100UG |
100 μg |
217.74 €
100 Mikrogramm |
Verfügbar ab: 07-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) is also known as Osteoclastogenesis inhibitory factor (OCIF), Osteoprotegerin (OPG). TNFRSF11B is a secreted homodimer protein, which can interact with TNFSF10 and TNFSF11. TNFRSF11B acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TNFRSF11B inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 70.2 kDa. The protein migrates as 90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_002537 | |
Human Osteoprotegerin, Fc Tag (TNB-H5259) is expressed from human 293 cells (HEK293). It contains AA Glu 22 - Leu 401 (Accession # NP_002537). | |
-20°C | |
Osteoprotegerin | |
Human | |
50 mM Tris, 100 mM Glycine, pH7.5 | |
HEK293 | |
Other Recombinant Proteins |
70.2 kDa | |
Glu 22 - Leu 401 | |
TNFRSF11B,OCIF,OPG,Osteoprotegerin | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>92% as determined by SDS-PAGE |