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ACROBiosystems Human P-Selectin / CD62P Protein, His Tag

Marke:  ACROBiosystems SEP-H52E4-100UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15887677

  • 296.52 € / 100 Mikrogramm
Verfügbar ab: 05-01-2023
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Beschreibung

Beschreibung

P-selectin (SELP) is also known as CD62 antigen-like family member P, granule membrane protein 140 (GMP-140), leukocyte-endothelial cell adhesion molecule 3 (LECAM3) and platelet activation dependent granule-external membrane protein (PADGEM). SELP functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets SELP is stored in α-granules. The primary ligand for SELP is P-selectin glycoprotein ligand-1 (PSGL-1) which is expressed on almost all leukocytes, although P-selectin also binds to heparan sulfate and fucoidan. Furthermore, SELP has a functional role in metastasis of tumor similar to E-selectin, which can help cancer cells invade into bloodstream for metastasis and provided locally with multiple growth factors respectively.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 81.8 kDa. The protein migrates as 110-125 kD under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

AAN06828
81.8 kDa
100 µg
Trp 42 - Ala 771
P-Selectin,CD62P,SELP,GMP-140
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human P-Selectin, His Tag (SEP-H52E4) is expressed from human 293 cells (HEK293). It contains AA Trp 42 - Ala 771 (Accession # AAN06828).
-20°C
P-Selectin
His Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote