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STEMCELL Technologies Human Recombinant IFN-alpha 2A

Código de producto. 17139511
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Menge:
100 μg
20 μg
Tamaño de la unidad:
100 Mikrogramm
20 Mikrogramm
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Código de producto. Menge unitSize
17139511 20 μg 20 Mikrogramm
17149511 100 μg 100 Mikrogramm
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Código de producto. 17139511 Proveedor STEMCELL Technologies N.º de proveedor 78076

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Descripción

Interferon-alpha 2A

  • Interferon-alpha (IFN-α) is a type I interferon, produced by virus-infected cells, and is released as a soluble factor to initiate antiviral responses (Isaacs & Lindenmann)
  • IFN-α2 is the most potent IFN-α used in fundamental research and in most clinical applications
  • The best-known IFN-α2 subvariants, 2A and 2B, differ by only one or two amino acids at positions 23 and/or 34 of the mature protein (von Gabain et al.) Type I IFNs exert potent antitumor activity by increasing the cytotoxic activity of NK and T cells, as well as by inhibiting the proliferation of cancer cells (Paul et al.) Additionally, it has been shown that proinflammatory IFN-α modulates the function of B cells in patients with systemic lupus erythematosus (Chang et al.), and pegylated forms of IFN-alpha 2A and 2B have implications in the treatment of hepatitis C (Foster et al.)

Especificaciones

Name IFN-alpha 2, IFNA2, IFNA2a
Menge 20 μg
Zelltyp B Cells; Cancer Cells and Cell Lines; NK Cells; T Cells
Reinheits- oder Qualitätsgrad ≥95%
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