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ACROBiosystems Human S100B Protein, His Tag

Marke:  ACROBiosystems S1B-H5143-100UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15897637

  • 285.12 € / 100 Mikrogramm
Verfügbar ab: 23-12-2022
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Beschreibung

Beschreibung

S-100 protein beta chain (S100B),a member of the S-100 family, is also known as S-100 protein subunit beta and S100 calcium-binding protein B, which contains two EF-hand domains. S100B can weakly bind calcium but bind zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Also, S100B can bind to and initiate the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction,S100B may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Fuethermore,S100B could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. S100B may mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 11.5 kDa. The protein migrates as 11 kDa under reducing (R) condition (SDS-PAGE).
Spezifikation

Spezifikation

NP_006263
11.5 kDa
100 µg
Ser 2 - Glu 92
S100B,NEF,S100,S100beta
Unconjugated
50 mM Tris, 150 mM NaCl, pH8.0
E.coli
Human
Powder
>95% as determined by SDS-PAGE
Human S100B, His Tag (S1B-H5143) is expressed from E.coli cells. It contains AA Ser 2 - Glu 92 (Accession # NP_006263).
-20°C
S100B
His Tag
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
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