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ACROBiosystems Human TNFR1 / CD120a / TNFRSF1A Protein, His Tag

Marke:  ACROBiosystems TN1-H5222-100UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15897797

  • 285.12 € / 100 Mikrogramm
Verfügbar ab: 11-01-2023
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Beschreibung

Beschreibung

Tumor necrosis factor receptor 1 (TNF-R1) is also known as Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), TNFAR, CD antigen CD120a, which belongs to the tumor necrosis factor receptor superfamily. TNF-R1 contains one death domain and four TNFR-Cys repeats. TNF-R1 is the receptor of TNFSF2 / TNF-alpha and homotrimeric TNFSF1 / lymphotoxin - alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNF-R1 contributes to the induction of non - cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Defects in TNFRSF1A are the cause of familial hibernian fever (FHF).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.3 kDa. The protein migrates as 28-40 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
Spezifikation

Spezifikation

NP_001056
22.3 kDa
100 µg
Ile 22 - Thr 211
TNFR1,CD120a,TNFRSF1A,FPF,TBP1,TNF-R,TNF-R-I,TNF-R55,TNFAR,TNFR55,TNFR60,p55,p60
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Human TNFR1, His Tag (TN1-H5222) is expressed from human 293 cells (HEK293). It contains AA Ile 22 - Thr 211 (Accession # NP_001056).
-20°C
TNFR1
His Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

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Sonderangebote