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Ivosidenib, MedChemExpress

Artikelnummer. 16497618
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Menge:
5 mg
10 mg
50 mg
100 mg
Unit Size:
100 Milligramm
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Product Code. 16497618

Brand: Medchem Express HY18767

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Description

MedChemExpress Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity.

Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity.

Specifications

Chemischer Name oder Material Ivosidenib
CAS 1448347-49-6
Farbe White
Hinweise zur Reinheitsqualität Research
Summenformel C28H22ClF3N6O3
Menge 10 mg
Synonym AG-120
Löslichkeitsinformationen DMSO : ≥ 39 mg/mL (66.90 mM)
SMILES ClC1=C([C@H](N(C2=CC(F)=CN=C2)C([C@H]3N(C4=NC=CC(C#N)=C4)C(CC3)=O)=O)C(NC5CC(F)(F)C5)=O)C=CC=C1
Molekulargewicht (g/mol) 582.96
Formelmasse 582.96
Reinheit (%) 98.01%
Güte Research
Physikalische Form Powder
Zur Verwendung mit (Anwendung) Cancer-programmed cell death
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Research purposes only

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