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JMY Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00 € - 399.00 €
Spezifikation
Antigen | JMY |
---|---|
Konzentration | 0.43 mg/mL |
Anwendungen | Immunoprecipitation, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot |
Klassifikation | Polyclonal |
Konjugat | Unconjugated |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
---|---|---|---|---|---|---|---|---|---|
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
16883635
|
Proteintech
25098-1-AP-20UL |
20 μL |
140.00 €
20 Mikroliter |
Verfügbar ab: 23-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
16873635
|
Proteintech
25098-1-AP-150UL |
150 μL |
399.00 €
150 Mikroliter |
Verfügbar ab: 23-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
JMY acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location.Spezifikation
JMY | |
Immunoprecipitation, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot | |
Unconjugated | |
Rabbit | |
Mouse, Rat, Human | |
Q8N9B5, Q9QXM1 | |
133746, 57748, 683593 | |
JMY Fusion Protein Ag18735 | |
Primary | |
-20°C | |
JMY |
0.43 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
JMY, WHDC1L3 | |
Jmy | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |