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Kir2.1 (KCNJ2) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA539218
Weitere Details : Netto-Gewicht : 0.00900kg
Beschreibung
The KIR2 subunit family includes 2.1, 2.2, 2.3 and 2.4. Unlike G protein-coupled KIR3 subunits, KIR2.1 requires both phosphorylation by PKA and ATP hydrolysis for functional activity. KIR2.1 is expressed in the superior and inferior collicula and the pontine region of the brain, where it moderates synaptic transmission, like many other potassium channels. In the placenta, KIR2.1 is expressed throughout gestation in cytotrophoblast cells. In the kidney, KIR2.1 colocalizes with KIR5.1 in the proximal tubule. KIR2.1, 2.2 and 2.3 associate with the membrane-associated guanylate kinase synapseassociated protein 97 in the cerebellum and heart. Phosphorylation of KIR2.2 by protein kinase A inhibits the associates with SAP97.Spezifikation
Kir2.1 (KCNJ2) | |
Polyclonal | |
Unconjugated | |
KCNJ2 | |
HHBIRK1, HHIRK 1, HHIRK1, HIRK 1, HIRK1, Inward rectifier K, IRK 1, IRK-1, IRK1, IRK2, KCNJ2, KIR2.1, LQT 7, LQT7, Potassium channel, SQT 3, SQT3 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
29712, 3759 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin) | |
1 mg/mL | |
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P63252, Q64273 | |
KCNJ2 | |
A synthetic peptide derived from the internal region of human KCNJ2 | |
100 μg | |
Primary | |
Human, Rat | |
Antibody | |
IgG |