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![Invitrogen™ KIT [V654A] Recombinant Human Protein 100μg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
Invitrogen™ KIT [V654A] Recombinant Human Protein
KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis.
Marke: Invitrogen™ PR7738A
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. The clinically observed V654A mutant has been demonstrated to be resistant to inhibition with imatinib.
Spezifikation
| NP_000213, V654A | |
| 50mM Tris (pH 7.5), 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% Glycerol | |
| 100μg | |
| RUO - research use only | |
| KIT V654A | |
| Human | |
| His Tag | |
| Frozen |
| Enzyme and Protein Activity Assay, Kinase Assay, Protein Assays and Analysis, Protein Biology | |
| 53.2kDa | |
| Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. | |
| Cytoplasmic | |
| PDGFR Kinase Family | |
| Recombinant | |
| Baculovirus |