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L-Prolin, 99 %, Thermo Scientific Chemicals

Product Code. 11449512
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Product Code. 11449512 Supplier Thermo Scientific Alfa Aesar Supplier No. A10199.22
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Description

CAS: 147-85-3 | C5H9NO2 | 115.13 g/mol

L-Proline is used as asymmetric catalysts in organic synthesis and asymmetric aldol cyclization. It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes. It is a precursor of hydroxyproline in collagen. It is an active component of collagen and involved in the proper functioning of joints and tendons. It finds uses in pharmaceutical, biotechnological applications due to its osmoprotectant property. Further, it is used with ninhydrin in the chromatography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Anwendungen
L-Prolin wird als asymmetrischer Katalysator in der organischen Synthese und der asymmetrischen Aldol-Zyklisierung eingesetzt. Sie ist an der Michael-Zugabe von Dimethylmalonat zu alfa-beta-ungesättigten Aldehyden beteiligt. Sie ist ein Vorläufer von Hydroxyprolin im Kollagen. Sie ist ein aktiver Bestandteil von Kollagen und an der ordnungsgemäßen Funktion von Gelenken und Sehnen beteiligt. Aufgrund ihrer osmoprotektiven Eigenschaften findet sie Anwendung in pharmazeutischen und biotechnologischen Anwendungen. Außerdem wird sie mit Ninhydrin in der Chromatographie verwendet.

Löslichkeit
Löslich in Wasser und Ethanol. Unlöslich in Äther, Butanol und Isopropanol.

Hinweise
Hygroskopisch. Nicht kompatibel mit starken Oxidationsmitteln.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 147-85-3
Summenformel C5H9NO2
Molekulargewicht (g/mol) 115.13
MDL-Nummer MFCD00064318
InChI-Schlüssel ONIBWKKTOPOVIA-UHFFFAOYNA-N
Synonym l-proline, proline, l---proline, s-pyrrolidine-2-carboxylic acid, 2-pyrrolidinecarboxylic acid, --proline, --s-proline, 2s-pyrrolidine-2-carboxylic acid, prolinum, h-pro-oh
PubChem CID 145742
ChEBI CHEBI:17203
IUPAC-Name (2S)-pyrrolidin-2-Carbonsäure
SMILES OC(=O)C1CCCN1

Specifications

Chemischer Name oder Material L-Proline
Schmelzpunkt ∽225°C (decomposition)
Beilstein 80810
Löslichkeitsinformationen Soluble in water and ethanol. Insoluble in ether,butanol and isopropanol.
Dichte 1.36
Menge 100 g
Formelmasse 115.13
Empfindlichkeit Hygroskopisch

RUO – Research Use Only

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