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Epredia™ Lab Vision™ ALK (Anaplastic Lymphoma Kinase)/p80 Rabbit Monoclonal Antibody
Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ ALK (Anaplastic Lymphoma Kinase)/p80, Rabbit Monoclonal Antibody.
Marke: Epredia™ RM-9108-S1
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Beschreibung
Recognizes a human p80 protein, identified as a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in 30-50% of CD30+ large cell lymphomas (1). This rabbit monoclonal antibody can be used to detect p80 in these lymphomas and may also be used to detect a recently described subtype of large B cell lymphoma, which expresses the full-length ALK protein (2).Host Species: Rabbit
Clone: SP8
Isotype: IgG
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: Recombinant protein corresponding to a region which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript
Positive Control: Anaplastic lymphoma
Cellular Localization: Cytoplasmic + nuclear Clone SP8 is excellent for staining of formalin/paraffin with no special pretreatment
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Spezifikation
| ALK (Anaplastic Lymphoma Kinase)/p80 | |
| Monoclonal | |
| Unconjugated | |
| Recombinant protein corresponding to a region, which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript | |
| IVD | |
| Primary | |
| Concentrated |
| Immunohistochemistry (Paraffin) | |
| SP8 | |
| Rabbit | |
| 500 μL | |
| Cancer and Tumor Biology | |
| Human | |
| IgG |
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