Epredia™ Lab Vision™ CD138 Ab-2, Mouse Monoclonal Antibody

Beschreibung

CD138/Syndecan-1 is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. CD138 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is a selective marker for B cell lymphoblastic leukemia and lymphoplasmocytoid leukemia. It is lost from the apoptotic myeloma cells; hence, it is a useful marker for viable myeloma cells.

Host Species: Mouse

Clone: MI15

Isotype: IgG1/κ

Species Reactivity: Human. Others not known

Epitope: Ectodomain

Immunogen: U-266 cells

Molecular Weight: 30.5kDa (core protein); 85-92kDa (depending upon glycosaminoglycans)

Positive Control: U-266 cells, Tonsil

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunoprecipitation