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TAG-72/CA 72-4TM Ab-1 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ TAG-72/CA 72-4 Ab-1, Mouse Monoclonal Antibody.
Marke: Epredia MS-138-P
Weitere Details : Netto-Gewicht : 0.00250kg
Beschreibung
Tumor-associated glycoprotein (TAG-72) is an oncofetal antigen with properties of a mucin. About 60% of carcinoma patients express TAG-72 in their sera.
Host Species: Mouse
Clone: B72.3
Isotype: IgG1/κ
Species Reactivity: Human, Cow, Dog, Hamster and Rat. Others not known.
Epitope: Mucin-carried-sialylated-Tn epitope
Immunogen: Membrane-enriched fraction of a human breast carcinoma liver metastasis
Molecular Weight: >1000kDa
Positive Control: Breast or lung CA
Cellular Localization: Cell surface and cytoplasmic. The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for Ab-1 staining. Weak or no reactivity has been observed with most cell types of normal adult tissue excepting the secretory endometrium. Ab-1 is reportedly useful in distinguishing pulmonary adenocarcinomas (B72.3+) from pleural mesotheliomas (B72.3-).
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Flow Cytometry
- Radioimaging
Note:
USA: RUO; Int'l: RUO
Spezifikation
| TAG-72/CA 72-4 Ab-1 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 1 mL | |
| Cancer and Tumor Biology | |
| Bovine, Canine, Hamster, Human, Rat | |
| IgG2a κ |
| Flow Cytometry, Immunohistochemistry (Paraffin) | |
| B72.3 | |
| Unconjugated | |
| Membrane-enriched fraction of a human breast carcinoma liver metastasis | |
| RUO | |
| Primary | |
| Concentrated |