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  7. LE 135, Tocris Bioscience™

LE 135, Tocris Bioscience™

Catalog Number 18004732
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Menge:
10 mg
50 mg
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
155877-83-1
C29H30N2O2
438.571
YZZAIQOVMHVWBS-UHFFFAOYSA-N
chembl37708, 4-7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-5h-benzo e naphtho 2,3-b 1,4 diazepin-13-yl benzoic acid, d0x5wp, 4-5,7,7,10,10-pentamethyl-7,8,9,10-tetrahydro-5h-5,12-diaza-benzo 4,5 cyclohepta 1,2-b naphthalen-13-yl-benzoic acid, 4-5,7,7,10,10-pentamethyl-7,8,9,10-tetrahydro-5h-benzo e naphtho 2,3-b 1,4 diazepin-13-yl benzoic acid, 4-5,7,7,10,10-pentamethyl-8,9-dihydronaphtho 2,3-b 1, 4 benzodiazepin-13-yl benzoic acid, 4-5,7,7,10,10-pentamethyl-8,9-dihydronaphtho 2,3-b 1,4 benzodiazepin-13-yl benzoic acid
10410894
4-(5,7,7,10,10-pentamethyl-8,9-dihydronaphtho[2,3-b][1,4]benzodiazepin-13-yl)benzoic acid
CC1(CCC(C2=CC3=C(C=C21)N=C(C4=CC=CC=C4N3C)C5=CC=C(C=C5)C(=O)O)(C)C)C
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
155877-83-1
C29H30N2O2
438.571
YZZAIQOVMHVWBS-UHFFFAOYSA-N
chembl37708, 4-7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-5h-benzo e naphtho 2,3-b 1,4 diazepin-13-yl benzoic acid, d0x5wp, 4-5,7,7,10,10-pentamethyl-7,8,9,10-tetrahydro-5h-5,12-diaza-benzo 4,5 cyclohepta 1,2-b naphthalen-13-yl-benzoic acid, 4-5,7,7,10,10-pentamethyl-7,8,9,10-tetrahydro-5h-benzo e naphtho 2,3-b 1,4 diazepin-13-yl benzoic acid, 4-5,7,7,10,10-pentamethyl-8,9-dihydronaphtho 2,3-b 1, 4 benzodiazepin-13-yl benzoic acid, 4-5,7,7,10,10-pentamethyl-8,9-dihydronaphtho 2,3-b 1,4 benzodiazepin-13-yl benzoic acid
10410894
4-(5,7,7,10,10-pentamethyl-8,9-dihydronaphtho[2,3-b][1,4]benzodiazepin-13-yl)benzoic acid
CC1(CCC(C2=CC3=C(C=C21)N=C(C4=CC=CC=C4N3C)C5=CC=C(C=C5)C(=O)O)(C)C)C

Beschreibung

Selective RARβ antagonist

Retinoic acid antagonist; displays moderate selectivity for RARβ over RARα (Ki values are 0.22 and 1.4 μM respectively). Highly selective over RARγ and RXRα. Inhibits human HL-60 leukemia cell differentiation induced by Am80 (IC50 = 150 nM).
Chemischer Name oder Material LE 135
Menge 50 mg
Formelmasse 438.56
Reinheit (%) >97%
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