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LGI2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Thermo Scientific PA553555
Weitere Details : Netto-Gewicht : 0.02000kg
Beschreibung
Immunogen sequence: DLTHLSLANN HIKALPRDVF SDLDSLIELD LRGNKFECDC KAKWLYLWLK MTNSTVSDVL CIGPPEYQEK KLNDVTSFDY ECTTTDFVVH QTLPYQSVSV DTFNSKNDVY VAIAQPSMEN CMVLEW Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%.
The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.Spezifikation
LGI2 | |
Polyclonal | |
Unconjugated | |
Lgi2 | |
Kiaa1916; leucine rich repeat LGI family member 2; leucine-rich glioma-inactivated protein 2; Leucine-rich repeat LGI family member 2; leucine-rich repeat LGI family, member 2; leucine-rich, glioma inactivated 2; LGI1-like protein 2; Lgi2; LGIL2; mKIAA1916 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
55203 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry, Immunohistochemistry, Western Blot | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q8N0V4 | |
Lgi2 | |
Recombinant protein corresponding to Human LGI2 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only