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CD4 Mouse anti-Rat, Brilliant Violet 421, Clone: OX-35, BD Optibuild™
Mouse Monoclonal Antibody
Marke: BD Biosciences 740040
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
The OX-35 clone recognizes the CD4 antigen on most thymocytes, a subpopulation of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells), monocytes, macrophages, some dendritic cells, and microglia. CD4 is an antigen coreceptor on the T-cell surface that interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through it's association with the T-cell receptor complex and protein tyrosine kinase Lck. The OX-35 clone has been reported to bind to a different epitope of CD4 than that recognized by the W3/25 and OX-38 clones.
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.
Spezifikation
| CD4 | |
| Monoclonal | |
| 0.2mg/mL | |
| Cd4; CD4 antigen; p55; W3/25 antigen; T-cell surface glycoprotein CD4 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Rat | |
| IgG2a κ |
| Flow Cytometry | |
| OX-35 | |
| Brilliant Violet 421 | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Rat T-cell blasts | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only