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ACROBiosystems Mouse B7-H3 / CD276 Protein, His Tag
Marke: ACROBiosystems B73-M52H4-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.4 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_598744 | |
| 100 μg | |
| Val 29 - Phe 244 | |
| B7-H3,CD276,B7 homolog 3 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 25.4 kDa | |
| Mouse B7-H3, His Tag (B73-M52H4) is expressed from human 293 cells (HEK293). It contains AA Val 29 - Phe 244 (Accession # NP_598744). | |
| -20°C | |
| B7-H3 | |
| Mouse | |
| PBS, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |