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MRCK beta Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA538838
Weitere Details : Netto-Gewicht : 0.00900kg
Beschreibung
Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-alpha and beta (MRCK-alpha, beta) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-alpha can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-alpha can also influence neurite outgrowth promoted by Cdc42 and Rac.Spezifikation
MRCK beta | |
Polyclonal | |
Unconjugated | |
CDC42BPB | |
Serine/threonine-protein kinase MRCK beta, CDC42-binding protein kinase beta, CDC42BP-beta, DMPK-like beta, Myotonic dystrophy kinase-related CDC42-binding kinase beta, MRCK beta,Myotonic dystrophy protein kinase-like beta, CDC42BPB, KIAA1124 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
113960, 217866, 9578 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q9Y5S2, Q7TT50, Q7TT49 | |
CDC42BPB | |
A synthetic peptide derived from the internal region of human MRCKB | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |