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MSC Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA551015
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
MSC Polyclonal Antibody detects endogenous levels of MSC protein.
MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many musclespecific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to represses MyoD activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation.Spezifikation
| MSC | |
| Polyclonal | |
| Unconjugated | |
| MSC | |
| ABF1; ABF-1; Activated B-cell factor 1; activated B-cell factor 1, homolog of mouse musculin; activated B-cell factor-1; bHLHa22; Class A basic helix-loop-helix protein 22; Msc; Musculin; myogenic repressor; Myor | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 17681, 9242 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunohistochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O60682, O88940 | |
| MSC | |
| Synthesized peptide derived from the C-terminal region of human Musculin. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |