missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Zelllinien und Blutprodukte
  4. Zelllinien
  5. Lebende Zellkulturen
  6. 17344219

DiscoverX PathHunter™ U2OS INSRa Functional Assay

Artikelnummer. 17344219
Encompass
Change view
Click to view available options
Menge:
2 Fläschchen
Packungsgröße:
2 Ampullen
Product Code. Menge unitSize
17344219 2 Fläschchen 2 Ampullen
1 options
This item is not returnable. View return policy

Product Code. 17344219

Brand: DiscoverX 931008C3

Bitte Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute!

This item is not returnable. View return policy

Description

The PathHunter™ U2OS INSRa Functional Assay measures INSRa receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ U2OS INSRa Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated INSRa dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses PK-tagged INSRa and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay-Eingabe SH2 Recruitment
Zelllinie U2OS
Zur Verwendung mit (Anwendung) Cell Lines
Primärer Agonist Insulin, Human
Menge 2 Fläschchen
Zieleintrag INSRa
Zugriffsnummer NM_001079817
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.