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Paxillin Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 10029-1-IG-150UL
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Beschreibung
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.Spezifikation
| Paxillin | |
| Polyclonal | |
| Unconjugated | |
| PXN | |
| paxillin, PXN | |
| Rabbit | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 1.2 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P49023, Q8VI36 | |
| PXN | |
| Protein A | |
| RUO | |
| 19303, 5829 | |
| -20°C | |
| Liquid |
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