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Perilipin 5 Rabbit anti-Human, Mouse, Porcine, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 26951-1-AP-20UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16885275

  • 112.71 € / 20 Mikroliter

Verfügbar ab
16-06-2021

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Beschreibung

Beschreibung

Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE.
Spezifikation

Spezifikation

Perilipin 5
0.43 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q00G26, Q8BVZ1
LSDP5, OXPAT, Perilipin 5, PLIN5
Rabbit
IgG
20 μL
-20°C
Primary
100142670, 440503, 66968
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
PLIN5
Liquid
PLIN5
Perilipin 5 Fusion Protein Ag25272
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Porcine, Mouse, Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation