missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Phospho-ERK1/ERK2 (Tyr204) Monoclonal Antibody (B.742.5), Invitrogen™
Rabbit Monoclonal Antibody
Marke: Invitrogen MA515174
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with the corresponding phosphorylated residues of either JNK/SAPK or p38 MAP kinase.
ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways. When growth factors bind to the receptor tyrosine kinase, Ras interacts with Raf, the serine/threonine protein kinase and activates it as well. Once actived, Raf phosphorylates serine residue in 2 further kinases, MEK1/2, which in turn phosphorylates tyrosine/threonine in extracellular-signal regulated kinase (ERK) 1/2. Upon activation, the ERKs either phosphorylate a number of cytoplasmic targets or migrate to the nucleus, where they phosphorylate and activate a number of transcription factors such as c-Fos and Elk-1.Spezifikation
Phospho-ERK1/ERK2 (Tyr204) | |
Monoclonal | |
98 μg/mL | |
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5 | |
P21708, P27361, P28482, P40417, P63085, P63086, Q63844 | |
MAPK1, MAPK3, rl | |
Synthetic phosphopeptide corresponding to residues surrounding pThr202/Tyr204 of human p44 MAP kinase | |
200 μL | |
Primary | |
Drosophila, Human, Mink, Mouse, Non-human Primate, Porcine, Rat, Zebrafish | |
Antibody | |
IgG |
Flow Cytometry, Immunocytochemistry, Western Blot | |
B.742.5 | |
Unconjugated | |
MAPK3 | |
12559; 9030612K14Rik; AA407128; AU018647; BcDNA:RE08694; C78273; CG12559; CG12559-PA; CG12559-PC; CG12559-PD; CG12559-PE; CG12559-PG; CG12559-PH; CG12559-PI; CG18732; CT34260; CT39192; DERK; D-ERK; DERK-A; Diphospho-ERK; dm-dpERK; Dmel\CG12559; Dmel_CG12559; DmErk; DmERKA; DmERK-A; DmMAPK; dpERK; dp-ERK; dpERK1; dpMAPK; drosophila ERK; Dsor2; E(sina)7; EC2-1; EK2-1; enhancer of seven in absentia 7; ERK; Erk MAP kinase; Erk/Map kinase; ERK/rolled; Erk1; Erk-1; erk1 erk2; Erk1/2; ERK1b; ERK2; ERK-2; ERKA; ERK-A; ERT1; ERT2; Esrk1; extracellular signal-regulated kinase; extracellular signal-regulated kinase (ERK2); extracellular signal-regulated kinase 1; Extracellular signal-regulated kinase 2; extracellular signal-regulated kinase A; extracellular signal-regulated kinase-1; extracellular signal-regulated kinase-2; extracellular signal-related kinase 1; Extracellular-regulated kinase A; extracellular-signal-regulated kinase 2; Extracellular-signal-related kinase A; EY2-2; fi06b09; GroupI | |
Rabbit | |
Affinity chromatography | |
RUO | |
100153927, 116590, 26413, 26417, 3354888, 360144, 399480, 445013, 50689, 5594, 5595 | |
-20°C | |
Liquid |