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CD90.2 Rat anti-Mouse, Brilliant Violet 510, Clone: 53-2.1, BD Optibuild™
Rat Monoclonal Antibody
Marke: BD Biosciences 740102
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
The 53-2.1 monoclonal antibody specifically binds to the CD90.2 (Thy-1.2) alloantigen on thymocytes, most peripheral T lymphocytes, some intraepithelial T lymphocytes (IEL, DEC), epithelial cells, fibroblasts, neurons, hematopoietic stem cells, but not B lymphocytes, of most mouse strains. The 53-2.1 antibody has been reported not to crossreact with Thy-1.1 (e.g., AKR/J, PL), or with rat Thy-1. CD90 is a glycophosphatidylinositol-anchored membrane glycoprotein of the Ig superfamily that is involved in signal transduction. In addition, there is evidence that CD90 mediates adhesion of thymocytes to thymic stroma. The 53-2.1 antibody has been reported to block the binding of the Rat Anti-Mouse CD90.2 antibody (Clone 30-H12) to immobilized thymocyte membranes.
The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50-nm) filter set. BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser.
Spezifikation
| CD90.2 | |
| Monoclonal | |
| 0.2mg/mL | |
| Thy-1.2; T25; Thymus cell antigen 1, theta | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgG2a κ, IgG2a κ |
| Flow Cytometry | |
| 53-2.1 | |
| Brilliant Violet 510 | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Mouse Thymus / Spleen | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only