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ACROBiosystems Rhesus macaque Fc gamma RIII / CD16 Protein, His Tag
SPR & BLI verified
266.13 € - 2661.24 €
Spezifikation
| Zugriffsnummer | XP_014968661.2 |
|---|---|
| Molekulargewicht | 23.1 kDa |
| Quelle | Rhesus macaque CD16, His Tag (FC6-R52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Gly 206 (Accession # A3RFZ7-1). |
| Immunogen | Glu 21 - Gly 206 |
| Lagerungsbedingungen | -20°C |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
17186301
|
ACROBiosystems
FC6-R52H6-50UG |
50 μg |
266.13 €
50 Mikrogramm |
Verfügbar ab: 28-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
|
17176301
|
ACROBiosystems
FC6-R52H6-1MG |
1 mg |
2661.24 €
1 Milligramm |
Verfügbar ab: 28-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell type-specific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages.CD16a antigen is also known as Low affinity immunoglobulin gamma Fc region receptor III-A, Fc-gamma RIII-alpha. CD16b is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas CD16a is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placentaltrophoblasts.CD16a is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibodydependent cytotoxicity and clearance of immune complexes. Aberrant expression or mutations of CD16a is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.1 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| XP_014968661.2 | |
| Rhesus macaque CD16, His Tag (FC6-R52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Gly 206 (Accession # A3RFZ7-1). | |
| -20°C | |
| Fc gamma RIII / CD16 | |
| Rhesus Macaque | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Fc Receptors |
| 23.1 kDa | |
| Glu 21 - Gly 206 | |
| FCGR3 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |