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RNF144B/IBRDC2 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 26306-1-AP-150UL
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.Spezifikation
RNF144B/IBRDC2 | |
Polyclonal | |
Unconjugated | |
RNF144B | |
IBRDC2, KIAA0161, p53RFP, ring finger protein 144B, RNF144B | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
255488 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.3 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q7Z419 | |
RNF144B | |
RNF144B/IBRDC2 Fusion Protein Ag23679 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG |