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Invitrogen™ UBE2T Recombinant Rabbit Monoclonal Antibody (24GB2350)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA557815
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Beschreibung
UBE2T Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow
UBE2T is involved in the covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Functionally, UBE2T accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, catalyzes monoubiquitination, is involved in mitomycin-C (MMC)-induced DNA repair, and catalyzES monoubiquitination of FANCD2, a key step in the DNA damage pathway. Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.
Spezifikation
| UBE2T | |
| Recombinant Monoclonal | |
| 1.2 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q9CQ37, Q9NPD8 | |
| UBE2T | |
| A synthesized peptide derived from human HSPC150 (aa 15-74). | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 24GB2350 | |
| Unconjugated | |
| UBE2T | |
| 2700084L22Rik; C80607; Cell proliferation-inducing gene 50 protein; E2 ubiquitin-conjugating enzyme T; FANCT; HSPC150; HSPC150 protein similar to ubiquitin-conjugating enzyme; PIG50; RGD1310816; Ube2t; Ubiquitin carrier protein T; ubiquitin conjugating enzyme E2 T; ubiquitin conjugating enzyme E2T; ubiquitin-conjugating enzyme E2 T; ubiquitin-conjugating enzyme E2T; ubiquitin-conjugating enzyme E2T (putative); ubiquitin-protein ligase T | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 29089, 360847, 67196 | |
| -20°C | |
| Liquid |
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