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Ulixertinib, MedChemExpress

Artikelnummer. 16499387
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Product Code. 16499387 Supplier Medchem Express Supplier No. HY15816

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Description

MedChemExpress Ulixertinib (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.

Ulixertinib (BVD-523

Specifications

Chemischer Name oder Material Ulixertinib
CAS 869886-67-9
Farbe White
Hinweise zur Reinheitsqualität Research
Summenformel C21H22Cl2N4O2
Menge 5 mg
Synonym BVD-523 VRT752271
Löslichkeitsinformationen DMSO : 100 mg/mL (230.77 mM; Need ultrasonic)
SMILES O=C(C1=CC(C2=CC(NC(C)C)=NC=C2Cl)=CN1)N[C@@H](C3=CC=CC(Cl)=C3)CO
Molekulargewicht (g/mol) 433.33
Formelmasse 433.33
Reinheit (%) 98.44%
Güte Research
Physikalische Form Solid
Zur Verwendung mit (Anwendung) Cancer-Kinase/protease
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Research purposes only

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