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ACROBiosystems Human MBL Protein, His Tag
Marke: ACROBiosystems MBL-H5220-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.9 kDa. The protein migrates as 30-33 kDa under reducing (R) condition (SDS-PAGE).Spezifikation
| AAH96179 | |
| 100 μg | |
| Glu 21 - Ile 248 | |
| MBL,MBL2,MBP1,MBP-C,Collectin-1,COLEC1,HSMBPC,MBL2D,MBPD | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 25.9 kDa | |
| Human MBL, His Tag (MBL-H5220) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Ile 248 (Accession # P11226-1). | |
| -20°C | |
| MBL | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |