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ACROBiosystems Human ALK-7 Protein, His Tag
Marke: ACROBiosystems AL7-H52H5-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
ALK-7 (Activin receptor-like kinase 7) is also known as Activin receptor type-1C, ACTR-IC, ACVR1C. Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11.9 kDa. The protein migrates as 15-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_660302.2 | |
| 100 μg | |
| Glu 21 - Glu 113 | |
| ALK-7,ACTR-IC,ACVR1C | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 11.9 kDa | |
| Human ALK-7, His Tag (AL7-H52H5) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Glu 113 (Accession # Q8NER5-1). | |
| -20°C | |
| ALK-7 | |
| Human | |
| 20 mM Tris, 150 mM NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |