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CD106 Rat anti-Mouse, Unlabeled, Clone: 429 (MVCAM.A), BD

Rat Monoclonal Antibody

Marke:  BD Biosciences 553330

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15897148

  • 373.92 € / 1 Stück
Verfügbar ab: 19-12-2022
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Beschreibung

Beschreibung

The 429 monoclonal antibody specifically binds to both the long (∼110 kDa) transmembrane-spanning form and the truncated (∼47 kDa) GPI-linked form of vascular cell adhesion molecule-1 (VCAM-1, CD106). CD106 is constitutively expressed on bone marrow stromal cells, myeloid cells, and splenic dendritic cells. Its expression on endothelial cells is upregulated by inflammatory cytokines and in certain pathologic conditions. CD106 expression has also been detected on apoptotic thymocytes, splenocytes, and lymphoid cell lines. VCAM-1 is a counter-receptor for VLA-4 ( α;4 β; 1 integrin) and LPAM-1 ( α;4 β; 7 integrin), and the 429 antibody partially blocks VCAM-1-mediated binding functions. Source of the immunogen was the mouse preadipose cell line PA6.
Spezifikation

Spezifikation

CD106
Monoclonal
0.5mg/mL
Vcam-1; Vascular cell adhesion molecule 1; Vascular cell adhesion protein 1
Rat
Affinity Purified
RUO
Primary
Store undiluted at 4°C
Flow Cytometry
429 (MVCAM.A)
Unconjugated
Aqueous buffered solution containing ≤0.09% sodium azide.
Mouse preadipose cell line PA6
0.5 mg
Immunology
Mouse
IgG2a κ
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.