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CD123 Mouse anti-Human, FITC, Clone: 7G3, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 561694

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Artikelnummer. 15891239

  • 182.40 € / 1 Stück
Verfügbar ab: 02-01-2023
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Beschreibung

Beschreibung

Reacts with human CD123, the 70kDa IL-3 receptor α chain (IL-3Rα), which associates with the 120-140kDa β subunit. The β chain is shared with the receptors for interleukins IL-5 and GM-CSF. IL-3Rα is expressed on hematopoietic progenitors and plays an important role in hematopoietic progenitor cell growth and differentiation. This antibody has been reported to block the binding of 125I-IL-3 to high and low affinity IL-3 receptors. In functional experiments, this antibody was found to inhibit acute myeloid leukemia cell proliferation, basophil histamine release, endothelial cell-mediated IL-8 secretion, and neutrophil transmigration. This antibody has been reported to be useful for
immunoprecipitation, western blot and immunofluorescent staining for flow cytometry. At the Fifth HLDA Workshop, the human IL-3 receptor was designated CD123.

Spezifikation

Spezifikation

CD123
Monoclonal
FITC
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human IL-3Ra-transfected cells
25 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
7G3
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha
Mouse
Affinity Purified
RUO
Human
IgG2a κ
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.