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CD152 Mouse anti-Human, APC, Clone: BNI3, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 555855

Weitere Details : Netto-Gewicht : 0.02000kg

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Artikelnummer. 15888488

  • 589.38 € / 1 Stück
Verfügbar ab: 22-12-2022
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Beschreibung

Beschreibung

Reacts with the “cytolytic T lymphocyte-associated antigen”, CTLA-4. CTLA-4 is transiently expressed on activated CD28+ T cells and binds to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. This interaction appears to deliver a negative regulatory signal to the T cell. There are recent reports that indicate that CTLA-4 is also expressed on B cells when cultured with activated T cells, suggesting a possible role of CTLA-4 in the regulation of B-cell response. Immobilized BNI3.1 enhances T-cell proliferation induced by CD3 and CD28. Recent studies have showed that CD152 can be expressed by regulatory T (Treg) cells. It has been found this antibody can stain the
intracellular CD152 on the Treg cells after fixation and permeabilization of cells.

Host Species: Mouse
Clone: BNI3
Isotype: IgG2a κ
Species Reactivity: Human

Flow Cytometry, Intracellular Staining

Spezifikation

Spezifikation

CD152
Monoclonal
APC
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human CTLA4 Recombinant Protein
100 Tests
Immunology
Human
IgG2a κ
Flow Cytometry
BNI3
CTLA-4; AILIM; Cytotoxic T-lymphocyte protein 4
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.