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CD16 Mouse anti-Human, Brilliant Violet 786, Clone: 3G8, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 563689

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15892999

  • 340.86 € / 1 Stück
Verfügbar ab: 19-12-2022
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Beschreibung

Beschreibung

The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (Fc γRIII), a human NK cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes. The 3G8 antibody is reported (Vossebeld et al ., 1997) to increase intracellular calcium levels in human neutrophils by interacting with both Fc γRIIa and Fc γRIIIb molecules. This antibody has also been reported to induce homotypic neutrophil aggregation.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon™ BV786 can be excited by the violet laser and detected in a filter used to detect Cy7™-like dyes (eg, 780/60-nm filter).

Spezifikation

Spezifikation

CD16
Monoclonal
Brilliant Violet 786
Mouse
Affinity Purified
RUO
Rhesus Monkey, Human, Cynomolgus, Baboon
IgG1 κ
Flow Cytometry
3G8
FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3
Human polymorphonuclear leukocytes
25 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.