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Heme Oxygenase 1 Mouse anti-Human, Unlabeled, Clone: 23, BD
Mouse Monoclonal Antibody
308.08 € - 610.00 €
Spezifikation
Antigen | Heme Oxygenase 1 |
---|---|
Klon | 23 |
Konzentration | 250μg/mL |
Anwendungen | Western Blot |
Klassifikation | Monoclonal |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
---|---|---|---|---|---|---|---|---|---|
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15885599
|
BD Biosciences
610713 |
150 μg |
610.00 €
1 Set |
Verfügbar ab: 24-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
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15875599
|
BD Biosciences
610712 |
50 μg |
Dieser Artikel ist im Moment nicht verfügbar oder wird nicht mehr hergestellt. Schauen Sie bitte auf unsere Produktseite nach möglichen Alternativen |
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Beschreibung
Heme oxygenases 1 and 2 (HO-1, HO-2) cleave the heme molecule, resulting in the production of carbon monoxide (CO) and biliverdin. HO-1 is a 288 amino acid monooxygenase with a molecular weight of 32kDa. While HO-2 is constitutively expressed in tissues, HO-1 is rapidly induced by several stimuli such as lutathione depletion, hemin, heat shock, heavy metals, oxidative stress, oxidized LDL, anoxia, and endotoxic shock. Similar to nitric oxide (NO), CO activates guanylate cyclase and reduces platelet aggregation. Several conditions that increase NO also induce HO-1 expression and activity. This suggests that NO synthases, Cox-2, and HO-1 are part of a general defense mechanism against stress and pathogen invasion.
Immunofluorescence, Immunoprecipitation, Western Blotting
Spezifikation
Heme Oxygenase 1 | |
250μg/mL | |
Monoclonal | |
Mouse | |
Cell Biology | |
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
IgG1 | |
Affinity Purified |
23 | |
Western Blot | |
Unconjugated | |
RUO | |
Human | |
Human Heme Oxygenase 1 (HO-1) aa. 150-286 | |
Primary | |
Store undiluted at -20°C. |
For Research Use Only.