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STEMCELL Technologies ArciTect™ T7 Endonuclease I Kit

Artikelnummer. 17139311
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17129311 25 Reaktionen 1 Set
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Artikelnummer. 17139311

Marke: STEMCELL Technologies 76022

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Descrizione

For estimation of CRISPR-Cas9 genome editing efficiency

  • ArciTect™ T7 Endonuclease I is the preferred enzyme for detecting genome editing such as insertions or deletions (INDELs) generated by CRISPR-Cas9
  • ArciTect™ T7 Endonuclease I Kit is comprised of ArciTect™ T7 Endonuclease I and ArciTect™ T7 Endonuclease I Buffer (10X), which have been tested and validated for use with the ArciTect™ CRISPR-Cas9 genome editing system
  • ArciTect™ T7 Endonuclease I recognizes and cleaves mismatched DNA, cruciform DNA structures, Holliday structures or junctions, heteroduplex DNA, and, less efficiently, nicked double-stranded DNA
  • Since the cleavage efficiency is proportional to the number of INDELs created at a specific DNA target, ArciTect™ T7 Endonuclease I Kit is used to estimate gene-editing efficiency in a rapid and cost-effective manner

Specifica

Zur Verwendung mit (Anwendung) Estimation of CRISPR-Cas9 Genome Editing Efficiency
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