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ACROBiosystems Biotinylated Human TNF-alpha Protein, His,Avitag™ (active trimer)

MALS verified

Marke:  ACROBiosystems TNA-H82E3-200UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15887837

  • 1733.51 € / 200 Mikrogramm
Verfügbar ab: 12-01-2023
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Beschreibung

Beschreibung

Tumor necrosis factor alpha (TNFα) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 20.0 kDa. The protein migrates as 21 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_000585.2
20.0 kDa
200 µg
Val 77 - Leu 233
DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα
Precision Avi
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
MABSol™ Biotinylated Human TNF-alpha, His,Avitag (active trimer) (MALS verified) (TNA-H82E3) is expressed from human HEK293 cells. It contains AA Val 77 - Leu 233 (Accession # NP_000585.2).
-20°C
TNF-alpha
His Tag and Avi Tag
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote