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ACROBiosystems Cynomolgus / Rhesus macaque CD47 Protein, His Tag

Marke:  ACROBiosystems CD7-C52H1-50UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15886247

  • 399.17 € / 50 Mikrogramm
Verfügbar ab: 05-01-2023
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Beschreibung

Beschreibung

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.8 kDa. The protein migrates as 30-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_001253446.1
15.8 kDa
50 µg
Gln 19 - Glu 141
CD47,MER6,IAP,OA3
Unconjugated
PBS, pH7.4
HEK293
Cynomolgus / Rhesus macaque
Powder
>95% as determined by SDS-PAGE
Cynomolgus / Rhesus macaque CD47, His Tag (CD7-C52H1) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Glu 141 (Accession # F7A802-1). In the region Gln 19 - Glu 141, the AA sequence of Cynomolgus and Rhesus macaque CD47 are homologus.
-20°C
CD47
His Tag
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
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