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ACROBiosystems Human APRIL / TNFSF13 Protein, Fc Tag
Marke: ACROBiosystems APL-H5267-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
APRIL(a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFFSF 13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 42.8 kDa. The protein migrates as 48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_003799.1 | |
| 100 µg | |
| Ala 105 - Leu 250 | |
| APRIL,TNFSF13,TALL-2,TRDL-1,CD256,TALL2,ZTNF2 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / µg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 42.8 kDa | |
| Human APRIL, Fc Tag (APL-H5267) is expressed from human 293 cells (HEK293). It contains AA Ala 105 - Leu 250 (Accession # O75888-1). | |
| -20°C | |
| APRIL | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |